Interleukin-2 and Splenic Enlargement

The bedside assessment of splenic enlargement.

STUDY OBJECTIVE To evaluate the clinical assessment of splenic enlargement using specific bedside maneuvers including Traube's space percussion, the splenic percussion sign, Middleton's maneuver, supine palpation, and right lateral decubitus palpation. DESIGN Quasi-experimental prospective study of cases and controls selected according to the results of abdominal ultrasonographic examinations...

Splenic enlargement in congestive heart failure and active rheumatic infection.

It is generally stated that the spleen rarely if ever enlarges sufficiently to become palpable in uncomplicated congestive heart failure. Rolleston (1908) and Held (1919) both concluded that a palpable spleen in congestive failure was due to some complication. Talley and Lindsey (1924) in 198 cases ofcongestive failure in adults found 3 with palpable spleens. Fishberg (1940) in discussing the q...

Reliability of clinical techniques for detecting splenic enlargement.

Plant-produced Recombinant Human Interleukin-2 and Its Activity against Splenic Cd4 + T-cells

Recombinant human interleukin-2 (rhIL-2) is a biopharmaceutical protein of great importance, as it is the standard FDA-approved immunotherapeutic treatment for end-stage metastatic melanoma and renal cell cancer. In this study, we explored the feasibility of producing biologically active rhIL-2 in the green tissues of transgenic tobacco (Nicotiana benthamiana). Production of rhIL-2 proteins in ...

Effect of Vitamin D treatment on Interleukin-2 and Interleukin-4 Genes expression in Multiple Sclerosis

Introduction: Multiple sclerosis is a chronic inflammatory disease of central nervous system. The etiology of MS is slightly known, but genetic and environmental factors are reported. Vitamin D regulates gene expression and affects target cell functions. The aim of this study was to investigate the expression variation of IL-2 and IL-4 genes under vitamin D supplementation in patients with mult...